HAPSIM Simulate case-control association data with this tiny tool.
Download

HAPSIM Ranking & Summary

HAPSIM Tags

Analyze simulation simulate File Association Manage Association Create Association Association Association Manager action association dafault image association Display Association Association Builder Association Fixer Association Changer Change Association automate association control file association XnView association simulate proteomics data haplotype association test case-control association data bialleleic markers disease susceptibility locus haplotype association association test

HAPSIM Description

HAPSIM is a small, command prompt based application designed to simulate case-control association data where a disease susceptibility locus is potentially in tight linkage with a group of bialleleic markers which may be tightly linked with each other. The procedure consists of several stages and generates an output file containing equally sized samples of affected and unaffected individuals with their genotypes. The genotype at the disease susceptibility locus itself is not output but is used to generate the case and control phenotypes based on a user-specified disease model. The simulation process consists of five distinct phases: mutation to produce markers; recombination between markers; mutation to produce one or more disease alleles; recombination between disease and marker loci; sample selection conditional on a disease model.

HAPSIM Related Software