FBAT

Family Based Association Tests
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FBAT Ranking & Summary

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  • Rating:
  • License:
  • Freeware
  • Publisher Name:
  • Harvard School of Public Health
  • Operating Systems:
  • Windows All
  • File Size:
  • 382 KB

FBAT Tags


FBAT Description

FBAT is a small, handy tool specially designed to implement a broad class of Family Based Association Tests, adjusted for population admixture. Main features: Uses data from nuclear families, sibships, pedigrees, or any combination; provides unbiased tests with or without founder genotypes. Analyzes dichotomous, measured, or time-to-onset traits and multiple traits; trait definition can be optimized. Analyzes markers on the x-chromosome with same options as autosomal marker analysis Offers bi-allelic and multi-allelic tests of association using standard genetic models (additive, dominant, recessive or genotype). Offers large sample and Monte-Carlo exact tests of the null hypothesis: no linkage and no association; offers large sample test of H0: no association. Estimates allele frequencies; checks Mendelian consistency. Tests multiple markers using haplotypes; estimates haplotype frequencies and linkage disequilibrium between pairs of markers. Offers three multi-marker tests for testing multiple markers simultaneously, without resolving phase or assuming no recombination. Offers two multiple trait tests. Interactive and command driven program using standard pedigree data files; phenotype file is optional.


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